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Interactions
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"Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The
interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use.
"You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy." - U.S. National Institutes of Health "It took the Women’s Health Initiative trial around five years and $150 million to find that estrogen may be a problem after menopause," [Joseph S.] Dillon says. We have no such long-term studies of DHEA." - WebMD® |
| Category | Examples of Specific Terms |
| Interactions with Drugs | |
| Liver's enzyme system | Cytochrome P450 |
| Central nervous system agents | Carbamazepine and phenytoin |
| Blood sugar levels | Metformin (Glucophage®), drugs for diabetes by mouth, insulin |
| Blood clotting | anticoagulants (Blood thinners) or antiplatelet drugs (such as aspirin), warfarin (Coumadin®), heparin, and clopidogrel (Plavix®). Also smoking, oral contraceptives or hormone replacement therapy. |
| Heart rates or rhythm | Various heart medications or drugs, also alcohol. |
| Calcium channel blockers | Diltiazem (Cardizem®) and alprazolam (Xanax®) |
| Various Drugs | Canrenoate, anastrozole (Arimidex®), growth hormones, methylphenidale, amlodipine, nicardipine and other calcium channel blockers like diltiazem (Cardizem®) and alprazolam (Xanax®) |
| Hormonal therapies | Estrogen or androgen |
| Psychiatric drugs | Clozapine (Clozaril®) |
| Seizures or pain | GABA-receptor drugs |
| Influenza vaccination | Antibody titer |
| Drugs that Might Affect DHEA Levels | |
| Decrease | Dopamine, insulin, corticosteroids such as dexamethasone, drugs used to treat endometriosis such as danazol, opiate painkillers, antipsychotics, and estrogen-containing drugs. |
| Increase | Metopirone, alprazolam and benfluorex |
| Interactions with Herbs and Dietary Supplements | |
| Liver's enzyme system | Anything that affects the P450 system |
| Blood sugar levels | Arginine, cocoa, ephedra (when combined with caffeine), melatonin, aloe vera, American ginseng and bilberry |
| Blood clotting | Coenzyme Q10 or Panax ginseng, Ginkgo biloba, garlic, and saw palmetto |
| Heart rates or rhythm | adonis, balloon cotton, and foxglove/digitalis |
| Hormonal effects | Alfalfa, black cohosh, and bloodroot |
| Herbs and Supplement that Might Affect DHEA Levels | |
| Increase | Chromium picolinate |
| Miscellaneous Interactions | |
| Possibly addictive | Carnitine |
| Various | May increase melatonin secretion and prevent breakdown of vitamin E in the body |
| Various | Fiber, flavanoids, polyunsaturated fatty acids, probiotics, soy protein and yam |
Summarized from: U.S. National Institutes of Health
"Many other interactions are possible; check with a qualified healthcare
professional including a pharmacist, for a thorough list."
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The content presented in this website is for informational purposes only.
Before taking this or any other health supplement or therapy, consult your healthcare professional.
Even mild supplements can have varying effects on individuals, and can conflict with your existing medications and diet.
See additional information.
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